Activity Summary:
The Simply Speaking Hepatitis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Critical to achieving the elimination of HCV infection is identifying infected persons with improved screening and surveillance approaches and linking them to HCV care and treatment. These steps will reduce the incidence of HCV, cirrhosis, HCC, liver-related deaths, and retransmission of HCV. These slides review the changing epidemiology/demographics of HCV infection, burden of disease, and discusses screening and linkage-to-care approaches important to achieving the elimination of HCV infection in the United States.

Updated information is noted on the slide in the upper right-hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Persistent inflammation is a vexing phenomenon that contributes to comorbidities in persons with HIV as they live longer. Early initiation of ART is the cornerstone to minimizing harmful effects of HIV viremia and inflammation on target organ systems. In addition, greater attention is needed on preventative approaches to mitigate cardiovascular disease, renal insufficiency, bone disease/frailty, and cognitive decline. This activity will use a case-based approach to discuss age-related comorbidities in persons with HIV and prevention/management approaches for HIV and common comorbidities.

Updated information is noted on the slide in the upper right-hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking HIV Prevention lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Recognizing and discussing significant developments and strategies in HIV prevention places healthcare professionals at the forefront of HIV prevention and care. This slide set will review data presented at the 2018 HIV Research for Prevention Conference (HIVR4P) such as risk assessment, PrEP trials, new ART and PrEP delivery systems, and an update on vaccine research.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Recognizing and discussing significant developments and strategies in ART places healthcare professionals at the forefront of HIV care. This activity will explain how recent study results in ART apply to clinical practice and discuss significant developments and strategies in the management of persons with HIV. Included topics are HIV prevention, engagement in care, ART trials and new agents, adverse events and pregnancy.

Activity Summary:
The Simply Speaking Hepatitis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Chronic HCV infection affects over 3 million Americans and is a leading cause of liver failure, cirrhosis, and liver cancer. There are an increasing number of young patients and patients with milder disease than described in previous years. Understanding nuances of HCV disease in different patient populations require clinicians to become continually educated on the safe and appropriate use of direct-acting antiviral agents in clinical practice. These slides use a case-based format to discuss the contemporary management of HCV infection before and after the cure in treatment-naïve and experienced patients with various comorbidities.

Updated information is noted on the slide in the upper right-hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
We are pleased to have recently held the Atlanta Breast Cancer Symposium (ABCS) on April 13, 2019 at the InterContinental Buckhead in Atlanta, Georgia.

There are multiple professional education opportunities in breast cancer across the country. The difference of the ABCS with others is the emphasis in the molecular basis of breast cancer to be applied from early detection to management of advanced disease, beyond induction treatment.

The objective of the symposium is to educate the oncology community on the rapidly evolving field of breast cancer from molecular biology to the development and clinical application of highly specific molecules to interfere with the cellular machinery allowing the cancer cells to survive, proliferate, and spread.

These certified CME/CE enduring video archives, with panel discussions, provide access to the conference including clinical presentation and interactive panel discussions with the faculty and audience.

We hope you enjoy this activity!

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

The state-of-the-art approach to HIV management has evolved as regular advances in basic science and clinical research lay the foundation for future trends. This program will review current controversies in the field, including considerations for on-demand PrEP, antiretroviral treatment options for different patient profiles (treatment naïve vs experienced, comorbid conditions and women of child-bearing age), the clinical relevance of recent study results, and other hot topics in HIV clinical management.

Updated information is noted on the slide in the upper right-hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering data from January through March, 2019, will discuss HIV treatment, complications/side effect management and prevention strategies.

Activity Summary:
The national strategy for the elimination of HCV in the United States calls for a 90% reduction incidence of HCV and having 90% of those with HCV being treated. Significant strides have been achieved in simplifying HCV treatment regimens and improving SVR rates. Despite these advances, there are a number of challenging scenarios in HCV that require clinicians to become continually educated on the state-of-the-art approach to HCV management as well as safe and appropriate use of DAA regimens.

These Conversations in HCV will discuss the progress and barriers to achieving HCV elimination, challenging management issues in special patient populations, and strategies for HCV/HIV and HCV/HBV coinfection.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

These educational Quarterly Briefs will discuss changing guidelines, evolving treatment options, and side-effect considerations in the management of patients with HIV as well as an update on HIV prevention.

Activity Summary:
Recognizing and discussing significant developments and strategies in HCV therapy places healthcare professionals at the forefront of hepatitis care. This activity will explain how recent study results in HCV apply to clinical practice, discuss significant developments and strategies in HCV therapy, discuss results from key clinical studies on new antiviral therapy, and describe recent data on drug toxicity/adverse events, drug interactions, and strategies for HCV management.

These educational Clinical Clips will spotlight the latest advances in the prevention and treatment of hepatitis C through a series of daily, ‘what you need to know in 5-minutes’ videos each day from AASLD 2018.

Activity Summary:
Research shows that there is as much as a 2-year median lag between the time patients present with symptoms associated with PAH and a definitive diagnosis through right-heart catheterization. Millions of patients are seen annually in emergency and urgent care settings, often as their single point of contact with the US healthcare system.

These educational mini modules will outline the hallmarks of various forms of pulmonary hypertension, including PAH, in the hopes of triggering earlier referral for specific screening and diagnostic testing. In addition, recommendations for dealing with the already diagnosed PAH patient who presents for emergent/urgent care will be discussed.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the prevention and treatment of HIV through a series of ‘what you need to know in 5-minutes’ videos from HIV Drug Therapy, Glasgow.

Activity Summary:
The goal of PAH therapy should be not merely to lengthen a patient’s lifespan, but to allow them to fully participate in day-to-day activities. Traditional methods of monitoring patient progress on therapy and/or disease progression often overlook aspects of living that are most important to the patient. In addition, patients often are reluctant to discuss these matters with their clinicians.

These educational mini modules will outline quality-of-life measurements and patient-reported outcomes in PAH, how those measures intersect with traditional clinical outcomes, and how those measurements can be applied to clinical practice.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

These educational Quarterly Briefs will discuss changing guidelines, evolving treatment options, and side-effect considerations in the management of patients with HIV.

Activity Summary:
Despite dramatic advances in the development of treatments for pulmonary arterial hypertension (PAH), it remains a chronic life-threatening illness for which there is no cure. Advances in knowledge in the field are eagerly anticipated.

These educational Clinical Clips® will spotlight important research into the basic science, diagnosis, treatment, and medical management of patients with PAH based on data presented at the the American College of Chest Physicians Annual Meeting in San Antonio, Texas, October 6-10 2018, through a series of two ‘what you need to know in 5-minutes’ videos.

Activity Summary:
PAH is a rapidly progressive life-threatening condition in children. Improved awareness among primary care clinicians and others who care for children is essential to raise awareness of the differences in presenting symptoms and diagnostic screening for this rare condition compared with other common complaints.

These educational mini modules will outline screening and diagnosis, general care measures, and PAH-specific therapy, including children with congenital heart disease-related PH.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the prevention and treatment of HIV and viral hepatitis through a series of daily, ‘what you need to know in 5-minutes’ videos from the 22nd International AIDS Conference (AIDS 2018) in Amsterdam, The Netherlands.

Activity Summary:
Thrombocytopenia is a common manifestation among patients with chronic liver disease. In the setting of advanced liver disease, thrombocytopenia may negatively impact patient care by interfering with diagnostic and therapeutic procedures. The development of thrombopoietin agonists has the potential to provide clinicians with new options to improve patient care. However, current guidelines provide limited guidance on the optimal approach to increase platelet counts in patients with chronic liver disease.

These educational Mini Modules will outline the pathophysiologic mechanisms, platelet threshold levels, and other factors that impact the decision to initiate treatment for thrombocytopenia. In addition, the benefits and limitations of current and emerging therapeutic options will be discussed.

Activity Summary:
Despite dramatic advances in the development of treatments for pulmonary arterial hypertension (PAH), it remains a chronic life-threatening illness for which there is no cure. Advances in knowledge within field are eagerly anticipated.

These educational Clinical Clips will spotlight important research into the basic science, diagnosis, treatment, and medical management of patients with PAH based on data presented at the American Thoracic Society (ATS) International Conference in San Diego, California, May 19-23 2018, through a series of two ‘what you need to know in 5-minutes’ videos.

Activity Summary:
The introduction of cystic fibrosis transmembrane regulator (CFTR) modulator therapy represented a true break¬through in overcoming the genetic defects underlying cystic fibrosis (CF). Small-molecule therapy with a single agent, and a combination of that agent with a second complementary agent, has successfully improved meaningful clinical outcomes in patients with specific CF genotypes. This success has led to intensive research and development efforts to expand treatment options to broader populations of CF patients. As new agents become available, clinicians will need to make informed decisions about selecting appropriate therapy for individual CF patients.

These educational Mini Modules will outline the use of current CFTR modulator therapies, expectations for addressing unmet clinical needs with new therapies, and issues around integrating new therapies into clinical practice.

Activity Summary:
Recognizing and discussing significant developments and strategies in HCV therapy places healthcare professionals at the forefront of hepatitis care. This activity will explain how recent study results in HCV apply to clinical practice, discuss significant developments and strategies in HCV therapy, discuss results from key clinical studies on new antiviral therapy, and describe recent data on drug toxicity/adverse events, drug interactions, and strategies for HCV management.

These educational Clinical Clips will spotlight the latest advances in the prevention and treatment of hepatitis C through a series of daily, ‘what you need to know in 5-minutes’ videos each day from the 53rd Annual Congress of the European Association for the Study of the Liver (EASL).

Activity Summary:
We are pleased to have recently held the Optimal Management of HIV Disease & Hepatitis: Clinical Conference XXVI (OPMAN). The conference took place March 23-25, 2018, in Orlando, Florida with 15 of the leading clinicians and researchers in HIV and hepatitis medicine presenting an array of topics covering HIV disease, hepatitis and HIV-hepatitis coinfection. The presentations offered a unique distillation of clinically focused data tailored for practicing HIV and hepatitis healthcare professionals.

These certified CME/CE enduring video archives of OPMAN XXVI provide access to each day of the conference, including the clinical presentations, interactive case discussions and panel discussions addressing audience and faculty questions. CME/CE credit is provided separately by section so you can participate in only those sections of interest to you. We hope you enjoy this activity.

Activity Summary:
PAH patients have a wide variety of both ongoing and acute-care clinical needs. A variety of special clinical situations present themselves in this population.

These educational Mini Modules will outline clinical situations that include issues related to weight management and the development/recognition of sleep apnea in patients with PAH; treatment of atrial fibrillation/atrial flutter; preventing and managing acute respiratory infections; and issues related to the delivery of intravenous prostacyclins.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the prevention and treatment of HIV through a series of ‘what you need to know in 5-minutes’ videos, and a 1-hour webcast with data from each day of the CROI 2018.

Activity Summary:
Recently, modulators of the cystic fibrosis transmembrane regulator (CFTR) have been introduced as new therapy options for patients with cystic fibrosis (CF). Initial clinical experience with these agents indicates that their administration can be challenging to manage, being associated with adverse reactions in some patients. Some patients also have difficulty maintaining adherence to dosing regimens required for CFTR modulators and regimens involving co-administration of other chronic CF therapies.

This educational Mini Module will outline practical, clinically applicable approaches for minimizing and managing adverse events associated with CFTR modulators and for optimizing adherence.

Activity Summary:
New pan-genotypic regimens continue to transform HCV management with more potent, more convenient, and safer regimens. These rapid changes require clinicians to become continually educated on the state-of-the-art approach to HCV management as well as safe and appropriate use of these newer regimens.

These Conversations in HCV will discuss the use of 8- or 12-week HCV regimens in treatment-naïve patients, HCV management issue in contemporary difficult-to-cure patients, and considerations in the setting of renal disease, HCC, and transplantation.

Activity Summary:
This certified CME/CNE Interactive Case Review will address epidemiologic trends using a case-based approach to discuss optimal HCV therapy options and management approaches/challenges for patients with these various conditions.

Dr. Brown and Dr. Sulkowksi will discuss screening, prevention and treatment of hepatitis C virus (HCV) infection among special patient populations. Approaches necessary to achieve successful treatment of HCV in patients with HBV coinfection, HIV coinfection, advanced liver disease, and concomitant renal disease will be reviewed. Each Interactive Case has thought-provoking questions from the faculty built into the end giving users the opportunity to test their understanding of the material presented.

Activity Summary:
Management of the HIV/hepatitis-coinfected patient requires a multidisciplinary approach tailored to the treatment needs of HIV, hepatitis infection, or both and the potential ability of the patient to adhere to and tolerate treatment.

These educational mini modules will describe the epidemiology and significance of liver disease and hepatitis in HIV, explain the impact of ART on liver disease, and discuss current approaches to treating HCV and HBV infection in patients with HIV disease.

Activity Summary:
Even though treatment options for patients with PAH have greatly improved over the last several years, patients need to be closely monitored and therapy altered in order to avoid clinical deterioration.

These educational Mini Modules will outline how to monitor patients on initial PAH treatment to determine when patients need to have their PAH-specific therapy altered. Treatment regimens for the patient who has progressed or is at risk of disease progression will be discussed. The modules will also cover transplant wait-listing and other issues related to end-stage PAH.

Updated information is noted on the slide in the upper right-hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.