Activity Summary:
The Simply Speaking HIV Prevention lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Adolescents are a key population in the HIV epidemic, accounting for approximately 1 in 5 new HIV infection in the United States. The expanded indication for PrEP in adolescents (≥35 kg) provides clinicians with an additional, effective tool to further reduce the risk of HIV transmission in this group. Once diagnosed, youth with HIV are the least likely out of any age group to be linked to care and achieve viral suppression once on ART. The program will cover the spectrum of developmental changes in adolescents including social, behavioral, physiological and biological aspects and the impact of an HIV positive status. Prevention programs, considerations for PrEP use, testing, treatment, and support services among adolescents are also included.

Activity Summary:
Patient Perspectives in HIV: A CE Podcast Series is an accredited continuing education series of podcasts as downloadable audio files (MP3). These podcasts will be recorded and made available throughout the year.

In this series of podcasts, the content faculty and one of their patients will discuss considerations and challenges in the management of and treatment options for HIV. Topic covered will include special considerations for transgender patients, patients with multiple comorbidities and how patients have handled challenges in their management of HIV.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering HIV data from January through March of 2021 will discuss the most clinically relevant information including new drugs, investigational approaches to prevention, metabolic complications and co-infection with COVID-19.

Activity Summary:
Patient Perspectives in HIV Prevention: A CE Podcast Series is an accredited continuing education series of podcasts as downloadable audio files (MP3). These podcasts will be recorded and made available throughout the year.

The content faculty and one of their patients will discuss common considerations and challenges in the prevention of HIV. Topics covered include long-term experience with PrEP, patient considerations and barriers to PrEP, and how they’ve handled challenges.

Activity Summary:
Simply Speaking PAH includes a curriculum that highlights the very latest clinical data in pulmonary arterial hypertension. Slides are developed and updated throughout the year by leading PAH expert physicians. All content is reviewed and approved by the Simply Speaking PAH Planning Committee.

CTEPH is defined as PH in the presence of an organized thrombus within the pulmonary vascular bed that persists at least 3 months after the onset of anticoagulant therapy. The most commonly reported symptoms of CTEPH include exercise intolerance, fatigue, and dyspnea. Symptoms experienced by CTEPH patients are non-specific and often similar to those of other more common diseases, so CTEPH is under diagnosed and often misdiagnosed as another disease. CTEPH is potentially curable only with pulmonary endarterectomy (PEA) surgery, which is the treatment choice for patients who are surgical candidates. For patients who are not surgical candidates or who have persistent/recurrent CTEPH after PEA surgery, there is an approved medical therapy or percutaneous balloon pulmonary angioplasty (BPA). This slide kit covers diagnosis and emerging treatment strategies including sequencing and combination therapy.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking HIV Prevention lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

For the past 5 years, the number of persons newly infected with HIV has been consistent at approximately 38,000. But the CDC notes that 1 in 8 of the 1.2 million people living with HIV in the United States are unaware of their HIV status. PrEP (in conjunction with safe sex practices) is a critical part of primary prevention for individuals at high risk for HIV acquisition and tool to meet the HIV elimination targets in the United States. This activity will discuss the lessons learned from demonstration projects and open-label extension studies on approaches to mitigate potential barriers to PrEP uptake, strategies to improve integration of PrEP into existing clinical practices, and approaches to successfully start and maintain patients on PrEP.

Activity Summary:
Simply Speaking PAH includes a curriculum that highlights the very latest clinical data in pulmonary arterial hypertension. Slides are developed and updated throughout the year by leading PAH expert physicians. All content is reviewed and approved by the Simply Speaking PAH Planning Committee.

Patients seen in a typical rheumatology practice are at higher risk of PAH secondary to their conditions. Rheumatologists should maintain a high index of suspicion for PAH in their patients with systemic sclerosis and other mixed connective tissue disorders. This lecture will present recommendations for routine screening of patients in a rheumatology practice for PAH as well as the basics of diagnosis and management of PAH.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

This certified AMA/ANCC/ACPE webcast archive provides expert commentary by Dr. Paul Sax, highlighting the most clinically relevant information on HIV and common comorbidities from the 28th Conference on Retroviruses and Opportunistic Infections.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Patients living with HIV face multiple challenges. Listening and learning about concerns/barriers that patients with HIV face can improve individualized outcomes and expectations. This program will incorporate the patient voice to discuss, in a case-based format, the common healthcare and treatment needs of patients with HIV, translatability of recent study results to clinical practice, and strategies to improve patient outcomes.

Activity Summary:
Clinical Viewpoints PH-ILD includes a curriculum that highlights the very latest clinical data in pulmonary hypertension due to interstitial lung disease. Slides are developed and updated throughout the year by leading pulmonology expert physicians. Continue to visit the Lecture Library series throughout 2021 to view updates from new publications and conference updates. All content is reviewed and approved by the Clinical Viewpoints PH-ILD Planning Committee.

This activity is comprised of two clinical case scenarios to illustrate best-practice recommendations for diagnosis and further treatment and management of patients presenting with PH-ILD. The slides will provide guidance on safely and effectively integrating recent updates and evidence in PH-ILD into clinical practice.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

The number of older people with HIV is increasing, and those aging with HIV are experiencing an increasing burden of age-associated comorbidities. Although early initiation of ART is the cornerstone of therapy, greater attention is needed on preventative approaches to mitigate cardiovascular disease, renal insufficiency, bone disease/frailty, and cognitive decline. This activity will use a case-based approach to discuss age-related comorbidities in persons with HIV and prevention/management approaches for HIV and common comorbidities.

Activity Summary:
Simply Speaking PAH includes a curriculum that highlights the very latest clinical data in pulmonary arterial hypertension. Slides are developed and updated throughout the year by leading PAH expert physicians. All content is reviewed and approved by the Simply Speaking PAH Planning Committee.

Research shows that patients with PAH benefit greatly from early diagnosis and appropriate treatment. However, many patients face definitive diagnostic delays of two or more years. This activity is designed for primary care providers and other non-specialists, and incorporates case-based topics on diagnosis, differential diagnosis, right heart catheterization, risk assessment, treatment and patient perspectives.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
This certified CME/CNE activity features a recorded discussion among three experts reviewing new therapies and protocols to improve outcomes in (Graft Versus Host Disease) GVHD.

This educational activity will focus on the new therapies and protocols to improve outcomes in GVHD. Data will be reviewed and analyzed by expert faculty while discussing common patient scenarios and best practices in treatment.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of ‘what you need to know in 5-minutes’ videos from data presented virtually from the 28th Conference on Retroviruses and Opportunistic Infections.

Activity Summary:
Clinical Viewpoints PH-ILD includes a curriculum that highlights the very latest clinical data in pulmonary hypertension due to interstitial lung disease. Slides are developed and updated throughout the year by leading pulmonology expert physicians. Continue to visit the Lecture Library series throughout 2021 to view updates from new publications and conference updates. All content is reviewed and approved by the Clinical Viewpoints PH-ILD Planning Committee.

This activity is designed to provide an overview of the diagnosis, treatment, and management of patients presenting with PH-ILD. Latest evidence from completed and ongoing clinical trials will be presented to identify therapeutic approaches useful in reducing the symptom burden of afflicted patients. Current treatment paradigms, their limitations, and new developments in PH-ILD will also be discussed.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
Clinical Viewpoints PH-ILD includes a curriculum that highlights the very latest clinical data in pulmonary hypertension due to interstitial lung disease. Slides are developed and updated throughout the year by leading PH-ILD expert physicians. The Lecture Library offers various topics that can be accessed for AMA, ANCC or ACPE credit. Select your topic of interest and complete the pre/posttest and evaluation.

Continue to visit the Lecture Library series throughout 2021 to view updates from new publications and conference updates. All content is reviewed and approved by the Clinical Viewpoints PH-ILD Planning Committee.

Activity Summary:
The Simply Speaking PAH lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Outpatient management of PAH requires unique and practical considerations, especially for those who require implantable pumps. Further management decisions regarding chronic anti-coagulation therapy, exercise recommendations, travel considerations, medication adherence, respite, and psychosocial issues must also be addressed. This slide kit is designed for the multi-disciplinary medical team to address the practical challenges of managing PAH.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
Simply Speaking PAH includes a curriculum that highlights the very latest clinical data in pulmonary arterial hypertension. Slides are developed and updated throughout the year by leading PAH expert physicians. The Lecture Library offers various topics that can be accessed for AMA, ANCC or ACPE credit. Select your topic of interest and complete the pre/posttest and evaluation.

Continue to visit the Lecture Library series throughout 2021 to view updates from new publications and conference updates. All content is reviewed and approved by the Simply Speaking PAH Planning Committee.

Activity Summary:
The Clinical Viewpoints Hereditary Angioedema lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slides developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

The field of hereditary angioedema (HAE) has recently evolved with the advent of new and forthcoming diagnostic and treatment measures. In particular, the shift toward oral medications will most certainly improve the quality of life for HAE patients. This lecture provides an overview of current diagnostic and treatment procedures recommended by the World Allergy Organization (WAO) and the United States Hereditary Angioedema Association Medical Advisory Board (US HAEA MAB) and summarizes forthcoming new advances in the field of HAE.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:

This certified CME/CNE activity features a recorded discussion among three experts that reviews the latest research and options for the management of patients with MPNs.

This activity will feature Dr. Srdan Verstovsek, Dr. Ruben Mesa and Dr. John Mascarenhas discussing the standard of care for Polycythemia Vera and Myelofibrosis. The discussion will be supplemented by slides based on key discussion points which are available for download.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering data from October through December of 2020, will discuss recent data on updated HIV guidelines, ART trials, and COVID-19 and persons with HIV.

Activity Summary:

This certified CME/CNE activity features a recorded discussion among three lung cancer experts that reviews the latest options for the management of early stage lung cancer.

This activity will feature Dr. Jack West, Dr. Mark Socinski and Dr. Jamie Chaft discussing the standard of care for early stage lung cancer and recent data on the early use of immunotherapy for adjuvant or neoadjuvant use in early lung cancer. The discussion will be supplemented by slides based on the discussion which are available for download.

Activity Summary:
The Simply Speaking Rheumatoid Arthritis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Effective strategies for rheumatoid arthritis (RA) continue to evolve; however, there are no drugs that are universally effective for all patients. Management approaches for many clinical scenarios are not specifically/adequately addressed by current treatment guidelines, necessitating consideration of the most recent clinical trial data. Awareness of advances in RA knowledge base place healthcare professionals at the forefront of RA care. This activity will explain how recent study results in RA apply to clinical practice; discuss significant developments and strategies in RA pathogenesis, measurement, and therapy; and discuss results from key clinical studies on existing and investigational RA agents.

Activity Summary:

These certified CME/CNE interactive case presentations will review the latest management strategies and treatment options for the management of acute leukemia.

During these interactive case studies Dr. Richard M. Stone will address the most clinically relevant data on Acute Lymphoblastic Leukemia and Dr. Farhad Ravandi address the most clinically relevant data on Acute Myeloid Leukemia. Each Interactive Case has thought-provoking questions from the faculty built into them giving users the opportunity to test their understanding of the material presented.

Activity Summary:
Effective strategies for immune thrombocytopenia (ITP) continue to evolve and clinicians are often challenged when presented with clinical scenarios not adequately addressed by current treatment guidelines. Many times treatment decisions necessitate consideration of the most recent clinical trial data.

These educational Clinical Clips will highlight important advances in the medical management of patients with ITP based on data presented at the 62nd American Society of Hematology (ASH) Annual Meeting through a series of two ‘what you need to know in 5-minutes’ videos.

Activity Summary:
The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary arterial hypertension (PAH), altering routine standard of care practice. It is critical to balance the ongoing care and evaluation of PAH with the potential "exposure risk" to COVID-19.

In this presentation, Ronald Oudiz, MD and Murali Chakinala, MD, highlight the latest clinical updates on COVID-19 as well as current guidelines, protocols and resources to support people with PAH.

Activity Summary:
Recent progress in PAH is based on new strategies for combination therapy and on the escalation of treatments to improve the significant morbidity and mortality associated with this disease. This module is designed as a case-based discussion on the importance of monitoring patients to determine when and how to optimally alter their PAH therapy.

In case 1, Ronald Oudiz, MD discusses diagnosis, initial management, disease progression, and treatment escalation. In case 2, Sonja Bartolme, MD discusses how to manage the complications and precautions in a patient through pregnancy, labor and delivery, and the immediate postpartum period.

Activity Summary:
These certified CME/CE interactive case presentations will review new HIV treatment strategies for your practice.

Advances in therapeutic options and management approaches continues to transform the overall care of persons with HIV. This program will use an interactive case-based approach to discuss considerations when choosing new ART treatment strategies for persons with HIV.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

New information is constantly being learned about the novel coronavirus, COVID-19. These slides will cover recent studies of COVID-19 in people living with HIV and includes interim guidance from the Department of Health and Human Services.

Activity Summary:
We are pleased to have recently held the first virtual Optimal Management of HIV Disease & Hepatitis conference. This virtual conference was held in lieu of our typical in-person conference due to COVID-19. Despite this change, 15 leading clinicians and researchers in HIV and hepatitis medicine presented an array of topics covering HIV disease, hepatitis, HIV-hepatitis coinfection, and COVID-19. These presentations offered a unique distillation of clinically focused data tailored for practicing HIV and hepatitis healthcare professionals.

These certified CME/CE enduring video archives of OPMAN XXVIII provide access to each day of the conference, including clinical presentations, interactive case discussions, and panel discussions addressing audience and faculty questions. CME/CE credit is provided separately by section so you can participate in only those sections of interest to you. We hope you enjoy this activity.