Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering data from October through December of 2020, will discuss recent data on updated HIV guidelines, ART trials, and COVID-19 and persons with HIV.

Activity Summary:

This certified CME/CNE activity features a recorded discussion among three lung cancer experts that reviews the latest options for the management of early stage lung cancer.

This activity will feature Dr. Jack West, Dr. Mark Socinski and Dr. Jamie Chaft discussing the standard of care for early stage lung cancer and recent data on the early use of immunotherapy for adjuvant or neoadjuvant use in early lung cancer. The discussion will be supplemented by slides based on the discussion which are available for download.

Activity Summary:
The Simply Speaking Rheumatoid Arthritis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Effective strategies for rheumatoid arthritis (RA) continue to evolve; however, there are no drugs that are universally effective for all patients. Management approaches for many clinical scenarios are not specifically/adequately addressed by current treatment guidelines, necessitating consideration of the most recent clinical trial data. Awareness of advances in RA knowledge base place healthcare professionals at the forefront of RA care. This activity will explain how recent study results in RA apply to clinical practice; discuss significant developments and strategies in RA pathogenesis, measurement, and therapy; and discuss results from key clinical studies on existing and investigational RA agents.

Activity Summary:

These certified CME/CNE interactive case presentations will review the latest management strategies and treatment options for the management of acute leukemia.

During these interactive case studies Dr. Richard M. Stone will address the most clinically relevant data on Acute Lymphoblastic Leukemia and Dr. Farhad Ravandi address the most clinically relevant data on Acute Myeloid Leukemia. Each Interactive Case has thought-provoking questions from the faculty built into them giving users the opportunity to test their understanding of the material presented.

Activity Summary:
Effective strategies for immune thrombocytopenia (ITP) continue to evolve and clinicians are often challenged when presented with clinical scenarios not adequately addressed by current treatment guidelines. Many times treatment decisions necessitate consideration of the most recent clinical trial data.

These educational Clinical Clips will highlight important advances in the medical management of patients with ITP based on data presented at the 62nd American Society of Hematology (ASH) Annual Meeting through a series of two ‘what you need to know in 5-minutes’ videos.

Activity Summary:
The COVID-19 pandemic presents many unique challenges when caring for patients with pulmonary arterial hypertension (PAH), altering routine standard of care practice. It is critical to balance the ongoing care and evaluation of PAH with the potential "exposure risk" to COVID-19.

In this presentation, Ronald Oudiz, MD and Murali Chakinala, MD, highlight the latest clinical updates on COVID-19 as well as current guidelines, protocols and resources to support people with PAH.

Activity Summary:
Treatment choices for chronic immune thrombocytopenia (ITP) are complicated by the heterogeneity of the disease and the inability not only to diagnose it but also to objectively predict patient responses to treatment and outcomes. With lack of head-to-head clinical trial comparisons to guide therapeutic options and sequencing of treatment strategies, as well as the development of emerging agents, expert opinion is critical in guiding clinical decision-making. Furthermore, ITP in the elderly and pregnant patient poses considerable challenges, so specific individualized management strategies ideally should be considered to optimize outcomes.

Using patient case studies, James Bussel, MD and Hanny Al-Samkari, MD discuss real-life management of patients with chronic ITP.

Activity Summary:
Recent progress in PAH is based on new strategies for combination therapy and on the escalation of treatments to improve the significant morbidity and mortality associated with this disease. This module is designed as a case-based discussion on the importance of monitoring patients to determine when and how to optimally alter their PAH therapy.

In case 1, Ronald Oudiz, MD discusses diagnosis, initial management, disease progression, and treatment escalation. In case 2, Sonja Bartolme, MD discusses how to manage the complications and precautions in a patient through pregnancy, labor and delivery, and the immediate postpartum period.

Activity Summary:
These educational archived presentations will focus on issues related to HCV elimination among Appalachian community care providers. Topics discussed include approaches to identify patients at high risk, HCV screening and management strategies for persons who inject drugs and incarcerated persons, and gaps in the HCV care continuum and key tools that community healthcare professionals can use to achieve elimination goals within a clinical practice.

Dr. Sally Hodder and Dr. Alice Thornton will lead each of the 1-hour presentations along with a community expert in the each of the Appalachian regions.

Activity Summary:
These certified CME/CE interactive case presentations will review new HIV treatment strategies for your practice.

Advances in therapeutic options and management approaches continues to transform the overall care of persons with HIV. This program will use an interactive case-based approach to discuss considerations when choosing new ART treatment strategies for persons with HIV.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

New information is constantly being learned about the novel coronavirus, COVID-19. These slides will cover recent studies of COVID-19 in people living with HIV and includes interim guidance from the Department of Health and Human Services.

Activity Summary:
We are pleased to have recently held the first virtual Optimal Management of HIV Disease & Hepatitis conference. This virtual conference was held in lieu of our typical in-person conference due to COVID-19. Despite this change, 15 leading clinicians and researchers in HIV and hepatitis medicine presented an array of topics covering HIV disease, hepatitis, HIV-hepatitis coinfection, and COVID-19. These presentations offered a unique distillation of clinically focused data tailored for practicing HIV and hepatitis healthcare professionals.

These certified CME/CE enduring video archives of OPMAN XXVIII provide access to each day of the conference, including clinical presentations, interactive case discussions, and panel discussions addressing audience and faculty questions. CME/CE credit is provided separately by section so you can participate in only those sections of interest to you. We hope you enjoy this activity.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

This educational Clinical Clip will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with an archive of our webcast covering highlights of data presented virtually from HIV Glasgow and IDWeek 2020.

Activity Summary:
Effective strategies for rheumatoid arthritis (RA) continue to evolve and clinicians are often challenged when presented with clinical scenarios not adequately addressed by current treatment guidelines. Many times treatment decisions necessitate consideration of the most recent clinical trial data.

These educational Clinical Clips will highlight important advances in the medical management of patients with RA based on data presented at ACR Convergence 2020 through a series of three ‘what you need to know in 5-minutes’ videos.

Activity Summary:
These certified CME/CE interactive case presentations will review the latest management strategies and options for the prevention and treatment of HIV.

The management of the heavily treatment-experienced patient increasingly requires ART optimization to achieve or maintain viral suppression with minimal impact on tolerability, resistance, drug-drug interactions, and comorbid conditions. This program will use an interactive case-based approach to discuss ART management considerations for heavily treatment-experienced persons with HIV.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

This educational Clinical Clip will spotlight the latest advances in the treatment and prevention of HIV and related comborbidities, with a video of ‘what you need to know in 15-minutes’ from data presented virtually from IDWeek 2020.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering data from July through September of 2020, will discuss recent data on PrEP, pregnancy, changes in weight and COVID-19 in people with HIV.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of ‘what you need to know in 5-minutes’ videos from data presented virtually from HIV Drug Therapy, Glasgow 2020.

Activity Summary:
Treatment paradigms for multiple myeloma have changed substantially over the last years with many advances in novel therapeutic approaches.

Presented by Dr. Joseph Mikhael of the Translational Genomics Research Institute, City of Hope Cancer Center, and Chief Medical Officer of the International Myeloma Foundation, the archived recording of the certified-CME/CNE 1-hour live webcast will cover recent updates in the standard of care and review the latest approved products and new research for the management of multiple myeloma.

Activity Summary:
Currently the South is the epicenter of the HIV epidemic in the United States. It experiences the greatest burden of HIV and deaths, and improvement is needed in providing HIV prevention services and care. Closing these gaps is essential to the health of people in the region and meeting the national goal of ending the HIV epidemic.

This series of CME/CNE/CPE webcast archives are presented by nationally recognized content experts who practice in the Southern United States. Geographically appropriate topics will be covered focusing on the prevention, diagnosis and treatment of HIV.

Activity Summary:
The Simply Speaking Rheumatoid Arthritis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

An array of targeted biologic therapies and new targeted oral small molecule agents have been approved to treat rheumatoid arthritis (RA). Many clinical scenarios necessitate collaborative decision-making to understand the appropriate role of existing and new treatments in the care for patients with RA. This activity will use a case-based approach to discuss clinical considerations impacting individualized therapy for patients with RA.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
These certified CME/CE interactive case presentations will review the latest management strategies and options for the prevention and treatment of HIV.

Management of HIV in women is multifactorial, encompassing issues related to HIV disease, ART selection and complications, and pregnancy/infant health. This program will use an interactive case-based approach to discuss HIV-related prevention and ART management considerations for affected women.

Activity Summary:
New frontiers for prostate cancer therapy continue to be explored, as underscored by evolving principles and new agents in development. To deliver state-of-the-art care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations. There is a need for those who treat prostate cancer to consider expert opinion and guidelines in the context of the needs and beliefs of individual patients, to tailor therapy, and achieve best results.

This educational program will review metastatic, hormone-sensitive prostate cancer, non-metastatic, castration-resistant prostate cancer, and prostate cancer local recurrence.

Activity Summary:
Advanced Topics in PAH is designed to delve more deeply into advanced topics related to the management of patients with PAH.

This educational lecture, presented by Dr. Sonja Bartolome, discusses cardiopulmonary rehabilitation/exercise training for patients with PAH; pre-and-post capillary PH, including issues related to treatment decision-making; and best practices for performing the right-heart catheterization in clinical practice for patients suspected of having PAH, or who are being followed while under therapy.

Activity Summary:
Advanced Topics in PAH is designed to delve more deeply into advanced topics related to the management of patients with PAH.

This educational lecture, presented by Dr. Ronald Oudiz, discusses cutting-edge research in PAH and provides case-based discussions on the importance of monitoring patients to determine when and how to optimally alter their PAH therapy.

Activity Summary:
The Simply Speaking Rheumatoid Arthritis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Prompt initiation of DMARD therapy results in higher rates of remission or low disease activity in patients with rheumatoid arthritis (RA). Despite significantly improved outcomes in RA, there is no cure—underscoring the need for individualized therapy, development of new agents, and approaches to prevent/cure RA. This activity will discuss new and emerging treatments for RA, data on when to initiate treatment as it relates to RA prevention, and clinical considerations impacting individualized therapy for patients with RA.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Recognizing and discussing significant developments and strategies in ART places healthcare professionals at the forefront of HIV care. This activity will highlight recent trial results presented at AIDS 2020 including topics on HIV prevention, ART trials and new agents, adverse events, pregnancy and an HIV cure update.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

This educational Clinical Clip will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with an archive of our webcast covering highlights of data presented virtually from the 23rd International AIDS Conference.

Activity Summary:
The 6th World Symposium for Pulmonary Hypertension (WSPH) held in Nice, France, summarized scientific advances, re-examined the current guidelines, reviewed the definitions, and debated future directions for PAH.

This educational lecture, presented by Dr. Franz Rischard, discusses the pivotal findings from this important international meeting including new definitions, potential genetic mutations underlying the development of PAH, new diagnostic and treatment algorithm insights, and risk assessment tools to monitor patient status and treatment response.

Activity Summary:
The webcast archive series includes a curriculum that highlights the very latest clinical data in pulmonary arterial hypertension. These presentations are developed and presented by key expert physicians and further reviewed and approved by the planning committee.