Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering data from April through June of 2020, will discuss recent data on COVID-19, linkage to care and new agents.

Activity Summary:
The Simply Speaking Rheumatoid Arthritis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Effective strategies for rheumatoid arthritis (RA) continue to evolve; however, there are no drugs that are universally effective for all patients. Management approaches for many clinical scenarios are not specifically/adequately addressed by current treatment guidelines, necessitating consideration of the most recent clinical trial data. Awareness of advances in RA knowledge base place healthcare professionals at the forefront of RA care. This activity will explain how recent study results in RA apply to clinical practice; discuss significant developments and strategies in RA pathogenesis, measurement, and therapy; and discuss results from key clinical studies on existing and investigational RA agents.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of ‘what you need to know in 5-minutes’ videos from data presented virtually from the 23rd International AIDS Conference.

Activity Summary:
The Simply Speaking RA lecture library includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert faculty. The slides will be continuously evaluated and updated for current relevance.

Activity Summary:
Advances in cancer research unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest and most relevant clinical data on the advances in the treatment and management of ovarian cancer with a series of ‘what you need to know in 5-minutes’ videos from data presented at the American Association for Cancer Research (AACR) Virtual Annual Meeting.

Activity Summary:
These certified CME/CE interactive case presentations will review the latest management strategies and options for the prevention and treatment of HIV.

With a dramatic improvement in life expectancy, more persons with HIV are living longer. However, many older persons with HIV have an increased burden of age-related comorbidities--many of which impact physical and cognitive function. This program will use an interactive case-based approach to discuss age-related comorbidities in persons with HIV and prevention/management approaches for HIV and common comorbidities.

Activity Summary:
These certified CME/CE interactive case presentations will review the latest management strategies and options for the prevention and treatment of HIV.

As therapy and our understanding of the HIV disease process progresses, so do our management approaches, as noted by the multiple updates issued by the DHHS and IAS-USA on their guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. This program will address the most clinically relevant data on four different topics HIV clinicians face in their clinic: new treatment options and strategies, comorbidity management in today’s aging HIV population, heavily treatment experienced patients, and special considerations for women living with HIV.

Activity Summary:
Effective strategies for rheumatoid arthritis (RA) continue to evolve and clinicians are often challenged when presented with clinical scenarios not adequately addressed by current treatment guidelines. Many times treatment decisions necessitate consideration of the most recent clinical trial data.

These educational Clinical Clips will highlight important advances in the medical management of patients with RA based on data presented at the European Congress of Rheumatology (EULAR) 2020 E-Congress through a series of three ‘what you need to know in 5-minutes’ videos.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Many factors may prevent marginalized persons from being tested for HIV, initiate/adhere to ART, and may increase the frequency of behaviors that put a person at risk for HIV transmission. To this end it is important for HIV care providers to be knowledgeable about specific HIV care needs of these individuals. This activity will use a case-based approach to discuss contemporary HIV management considerations in a number of scenarios, including pregnancy, HCV coinfection, incarceration, substance use disorders, transgender, and mental health concerns.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking HIV Prevention lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Once diagnosed, youth with HIV are the least likely out of any age group to be linked to care and achieve viral suppression once on ART. This program will discuss HIV epidemiologic trends among adolescents, awareness/perceptions of HIV and prevention, counseling needs/challenges for those at risk, and PrEP/treatment considerations.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking PAH lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Clinical management of the newly diagnosed patient with PAH requires a strong multidisciplinary team. This case-based lecture will cover the most-recent guidelines for initiating PAH therapy in the newly diagnosed as well as team roles in managing patients through the process of dealing with this life-threatening condition.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

The number of older people with HIV is increasing, and those aging with HIV are experiencing an increasing burden of age-associated comorbidities. Although early initiation of ART is the cornerstone of therapy, greater attention is needed on preventative approaches to mitigate cardiovascular disease, renal insufficiency, bone disease/frailty, and cognitive decline. This activity will use a case-based approach to discuss age-related comorbidities in persons with HIV and prevention/management approaches for HIV and common comorbidities.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking PAH lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Acute right ventricular failure can be a devastating complication of severe PAH. Because of the differences between the left and right sides of the heart, tools and techniques dealing with left-heart failure often do not apply in the setting of the right heart or may even be counter-productive. Intensive care management of RV failure in this setting is extremely complex. This lecture provides top-line expert consensus on managing acute RV failure, including bridge-to-transplant options.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering data from January through March of 2020 will discuss recent data from CROI, including clinical implications of low level viremia, special patient populations and new agents.

Activity Summary:
The Simply Speaking Hepatitis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

The national strategy for the elimination of HCV in the United States calls for a 90% reduction in the incidence of HCV and having 90% of those with HCV being treated. Scaling up HCV treatment in persons who inject drugs (PWIDs) and persons who are incarcerated is necessary to achieve HCV elimination targets.

These slides will review important issues for PWIDs and the incarcerated with HCV, including epidemiologic trends, prevention strategies, and AASLD recommendations for contemporary HCV management approaches/challenges and harm-reduction approaches.

Activity Summary:
The Simply Speaking PAH lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

While surgical resection of thromboembolic lesions may be curative, in clinical practice many patients are not appropriate candidates for surgery, especially those with distal lesions. In addition, some patients who have undergone successful surgery may continue to have residual pulmonary hypertension. Data on medical management of inoperable or residual CTEPH has begun to emerge and will be presented.

Activity Summary:
The Simply Speaking HIV Prevention lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

PrEP (in conjunction with safe sex practices) has emerged as a key part of primary prevention for individuals at high risk for HIV acquisition. However, PrEP is used by fewer than 20% of people who could benefit from it in the United States. This activity will discuss the lessons learned from demonstration projects and open-label extension studies on approaches to mitigate potential barriers to PrEP uptake, strategies to improve integration of PrEP into existing clinical practices, and approaches to successfully start and maintain patients on PrEP.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
The Simply Speaking HIV Prevention lecture library includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert faculty. The slides will be continuously evaluated and updated for current relevance.

Activity Summary:
The Simply Speaking PAH lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

New information is constantly being learned about the novel coronavirus, COVID-19. These slides will cover the latest clinical topic updates and perspectives as well as current guidelines, protocols and resources to support people with PAH.

As this is a rapidly evolving situation this website is being updated regularly.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Recognizing and discussing significant developments and strategies in ART places healthcare professionals at the forefront of HIV care. This activity will explain how recent study results presented from CROI 2020 apply to clinical practice, and discuss significant developments and strategies in the management of persons with HIV. Included topics are HIV prevention, ART trials and new agents, adverse events and pregnancy.

Activity Summary:
The Simply Speaking PAH lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Patients seen in a typical rheumatology practice are at higher risk of PAH secondary to their conditions. Rheumatologists should maintain a high index of suspicion for PAH in their patients with systemic sclerosis and other mixed connective tissue disorders. This lecture will present recommendations for routine screening of patients in a rheumatology practice for PAH as well as the basics of diagnosis and management of PAH.

Activity Summary:
The Simply Speaking Hepatitis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Critical to achieving the elimination of HCV infection is identifying HIV-infected persons with improved screening and surveillance approaches and linking them to HCV care and treatment. These steps will reduce the incidence of HCV, cirrhosis, HCC, liver-related deaths, and retransmission of HCV. These slides will review the changing epidemiology/ demographics of HCV infection and burden of disease and discusses screening and linkage-to-care approaches important to achieving the elimination of HCV infection in the United States.

Activity Summary:
The Simply Speaking HIV Management lecture library includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert faculty. The slides will be continuously evaluated and updated for current relevance.

Activity Summary:
The Simply Speaking PAH lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Research shows that patients with PAH benefit greatly from early diagnosis and treatment. However, patients often face delays of two years or longer from the onset of symptoms before a definitive diagnosis of PAH is reached. Designed for primary care providers and other non-specialists, this case-based, interactive lecture will cover the basics of the diagnosis of PAH, including discussions of the most-common alternative/incorrect diagnoses received by patients.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

New information is constantly being learned about the novel coronavirus, COVID-19. These slides will cover the current interim guidance from the Department of Health and Human Services regarding the known risk factors for severe illness or hospitalization due to COVID-19 and how to support people who are infected with HIV.

Activity Summary:

Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of ‘what you need to know in 5-minutes’ videos from data presented at the 27th Conference on Retroviruses and Opportunistic Infections in Boston, Massachusetts.

Activity Summary:
The Simply Speaking Hepatitis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Achieving a sustained virologic response (SVR) is expected to benefit nearly all persons with chronic HCV infection. Despite the recommendation for treatment of nearly all patients with HCV infection, it remains critical for clinicians to understand patient- and disease-related factors that place individuals at risk for HCV-related complications as well as for HCV transmission. It is important that clinicians recognize the unique dimensions of HCV disease and its natural history in these populations when considering HCV regimen options. These slides will use a case-based format to review the contemporary management of HCV infection before and after the cure in treatment-naïve and experienced patients with various comorbidities.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering data from October through December 2019 will discuss recent data from IDWeek, EACS and recent guideline updates to include HIV treatment considerations and complications.

Activity Summary:
Non-alcoholic steatohepatitis (NASH) is a growing cause of cirrhosis, HCC, and liver transplantation. Treatment options for NASH remain limited. Management of NASH typically focuses on treating liver disease and associated metabolic comorbidities. However, no single treatment approach has proved universally applicable to the general population with NASH. Given the biologic complexity of NASH and its heterogeneity, it is unlikely that only one drug will be sufficient to treat all patients.

These educational Conversations in NASH will discuss the current and future burden of disease due to NASH, the potential noninvasive testing modalities for diagnosis and staging of disease, important management considerations, and the latest clinical data for the treatment of NASH.

Activity Summary:
Effective strategies for rheumatoid arthritis (RA) continue to evolve and clinicians are often challenged when presented with clinical scenarios not adequately addressed by current treatment guidelines. Many times treatment decisions necessitate consideration of the most recent clinical trial data.

These educational Clinical Clips will highlight important advances in the medical management of patients with RA based on data presented at the 2019 American College of Rheumatology/Association of Rheumatology Professionals Annual Meeting in Atlanta, GA, November 8-13, 2019 through a series of three ‘what you need to know in 5-minutes’ videos.