Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering HIV data from July through September of 2021 will discuss the most clinically relevant information including HIV prevention, novel agents, and ART considerations such as durability, metabolic effects and switching therapies.

Activity Summary:
These accredited continuing education interactive case presentations will review the latest management strategies and options for the prevention and treatment of HIV.

This interactive case review will use a case-based approach to discuss contemporary HIV management considerations in several patient case reviews, including injection drug use, transgender patients, HIV/HCV coinfection and multiple comorbidities.

Activity Summary:
This educational archived webcast features Dr. Robert Brown and Dr. Anthony Martinez presenting current cases and topics on today's HCV patient.

Activity Summary:
This accredited continuing education activity features a recorded discussion among three experts and is designed to keep healthcare professionals abreast of the most recent clinical findings in pulmonary arterial hypertension (PAH).

In this edition, Dr. Ronald Oudiz, Dr. Aaron Waxman and Dr. Marius Hoeper discuss past and future challenges of the World Symposium on Pulmonary Hypertension (WSPH), cardiopulmonary exercise testing in PH and the unmet clinical needs in systemic sclerosis-associated PAH (SSc-PAH).

Activity Summary:
Currently the South is the epicenter of the HIV epidemic in the United States. It experiences the greatest burden of HIV and deaths, and improvement is needed in providing HIV prevention services and care. Closing these gaps is essential to the health of people in the region and meeting the national goal of ending the HIV epidemic.

This accredited continuing education webcast archive was presented by nationally recognized content experts who practice in the Southern United States. Geographically appropriate topics and practical strategies such as improving engagement in care, the best ART options for patients, and challenges patients may face in interacting with their care team were discussed.

Activity Summary:
The Simply Speaking HIV Management lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Recognizing and discussing significant developments and strategies in ART places healthcare professionals at the forefront of HIV care. This slide set, developed by Dr. David Hardy, will highlight the most clinically relevant presentations from the 11th IAS conference, including COVID-19 and HIV, the latest HIV epidemiology data, HIV prevention, ART trials, and new agents.

Activity Summary:
Improvements in the care of pulmonary arterial hypertension (PAH) patients depends on improving clinician awareness of the latest research into new diagnostic techniques, medications, and monitoring.

In this video, Jean Elwing, MD and David Badesch, MD discuss topics on diagnosis, differential diagnosis, right heart catheterization, risk assessment, treatment and patient perspectives in PAH.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

This certified AMA/ANCC/ACPE webcast archive provides expert commentary by Dr. David Hardy highlighting the most clinically relevant information on HIV from the 11th IAS Conference on HIV Science.

Activity Summary:
These educational presentations will focus on issues related to HCV elimination among Appalachian community care providers. Topics discussed include approaches to identify patients at high risk, HCV screening and management strategies for persons who inject drugs and incarcerated persons, and gaps in the HCV care continuum and key tools that community healthcare professionals can use to achieve elimination goals within a clinical practice.

Dr. Sally Hodder and Dr. Alice Thornton will lead each of the 1-hour presentations along with a community expert in the each of the Appalachian regions. The webcast archive will be available for 1 AMA/ANCC/ACPE credit/contact hour(s) based on confirmed participation and the completion of an evaluation and posttest.

Activity Summary:
This educational archive features Dr. Mark Sulkowski and Dr. Stacey Trooskin presenting topics on today's HCV patient using cases submitted by the audience.

Activity Summary:
The Simply Speaking Hepatitis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

The national strategy for the elimination of HCV in the United States calls for a 90% reduction in the incidence of HCV and having 90% of those with HCV being treated. Scaling up HCV treatment in persons who inject drugs (PWIDs) and persons who are incarcerated is necessary to achieve HCV elimination targets.

These slides will review important issues for PWIDs and the incarcerated with HCV, including epidemiologic trends, prevention strategies, and AASLD recommendations for contemporary HCV management approaches/challenges and harm-reduction approaches.

Activity Summary:
The Simply Speaking Hepatitis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Critical to achieving the elimination of HCV infection is identifying HIV-infected persons with improved screening and surveillance approaches and linking them to HCV care and treatment. These steps will reduce the incidence of HCV, cirrhosis, HCC, liver-related deaths, and retransmission of HCV. These slides will review the changing epidemiology/ demographics of HCV infection and burden of disease and discusses screening and linkage-to-care approaches important to achieving the elimination of HCV infection in the United States.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering HIV data from April through June of 2021 will discuss the most clinically relevant information including HIV mortality, COVID-19, ART guidelines and recent studies, weight gain and PrEP.

Activity Summary:
Effective strategies for immune thrombocytopenia (ITP) continue to evolve and clinicians are often challenged when presented with clinical scenarios not adequately addressed by current treatment guidelines. Many times treatment decisions necessitate consideration of the most recent clinical trial data.

These educational Clinical Clips will highlight important advances in the medical management of patients with ITP based on data presented at the 2021 International Society on Thrombosis and Haemostasis (ISTH) Virtual Congress.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of ‘what you need to know in 5-minutes’ videos from data presented virtually from the 11th IAS Conference on HIV Science.

Activity Summary:
Immunotherapy approaches have revolutionized the treatment of melanoma and ongoing studies are focused on improving outcomes and reducing toxicities with existing and novel therapies. To ensure updated ongoing care for patients, clinicians need to stay abreast with recent clinical trial evidence from different settings of melanoma treatment.

This educational Clinical Clip will highlight important advances in immunotherapy approaches for melanoma based on data presented at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting.

Activity Summary:
Patient Perspectives in HCV is an educational podcast comprising a series of episodes released throughout the year.

These interview-based podcasts will focus on the patient's life experience with HCV infection, including diagnosis, interactions with healthcare providers, top treatment concerns, and how life changed since being cured. The series will also discuss approaches to improve HCV outcomes based on lessons learned from these patient perspectives.

Activity Summary:
Patient Perspectives in HIV: A CE Podcast Series is an accredited continuing education series of podcasts as downloadable audio files (MP3). These podcasts will be recorded and made available throughout the year. The content faculty and one of their patients will discuss common considerations and challenges in HIV.

In this podcast, Dr. Babafemi Taiwo and a patient will discuss challenges and management strategies in the setting of multiple comorbidities and multi-drug resistance.

Activity Summary:
NAFLD and resulting NASH are highly prevalent globally and in the United States, where they are a growing cause of cirrhosis, HCC, and increasingly an indicator for liver transplantation. The total burden of disease due to NASH will likely rise for the next 15 years.

These educational Clinical Clips will spotlight the latest and most relevant clinical data in the advances in the treatment and management of non‐alcoholic steatohepatitis (NASH) with a series of ‘what you need to know’ videos from data presented at the virtual International Liver Congress from June 23‐26.

Activity Summary:
We are pleased to have recently held the second Optimal Management of HIV Disease & Hepatitis virtual conference. This virtual conference was again held in lieu of our typical in-person conference due to the COVID-19 pandemic. Despite this change, 15 leading clinicians and researchers in HIV and liver disease presented an array of topics covering ART, PrEP, hepatitis therapy, vaccines, HIV-hepatitis coinfection, substance abuse and mental health considerations. These presentations offered a unique distillation of clinically focused data tailored for practicing healthcare professionals.

These accredited enduring video archives of OPMAN XXIX provide access to each day of the conference, including clinical presentations, interactive case discussions, and panel discussions addressing audience questions. CME/CE credit is provided separately by section so you can participate in only those sections of interest to you. We hope you enjoy this activity.

Activity Summary:
This AMA/ANCC/ACPE activity features a recorded discussion among three experts and is designed to keep healthcare professionals abreast the most recent clinical findings in PAH.

The second edition will feature Dr. Ronald Oudiz, Dr. Nicholas Hill and Dr. Richard Channick discussing congress highlights from the International Society for Heart and Lung Transplantation and American Thoracic Society 2021, intensive care management of the PAH patient with COVID-19 and recent updates to the medical management of patients with CTEPH.

Activity Summary:
Currently the South is the epicenter of the HIV epidemic in the United States. It experiences the greatest burden of HIV and deaths, and improvement is needed in providing HIV prevention services and care. Closing these gaps is essential to the health of people in the region and meeting the national goal of ending the HIV epidemic.

This AMA/ANCC/ACPE webcast archive is presented by nationally recognized content experts who practice in the Southern United States. Geographically appropriate topics and practical strategies on prevention, screening, barriers to prevention and access to care will be discussed.

Activity Summary:
These certified CME interactive case presentations will review recent clinical trial and published data that will support the appropriate management and treatment decisions recommended by the expert faculty in multiple myeloma.

During these interactive case presentations Dr. Joseph Mikhael and Dr. Nina Shah will address scenarios focusing on a newly diagnosed patient, early relapse, late relapse and patient requiring maintenance therapy, will be presented and discussed. The activity will be supported by downloadable slides that have the key discussion/teaching points.

Activity Summary:
Effective strategies for immune thrombocytopenia (ITP) continue to evolve and clinicians are often challenged when presented with clinical scenarios not adequately addressed by current treatment guidelines. Many times treatment decisions necessitate consideration of the most recent clinical trial data.

These educational Clinical Clips will highlight important advances in the medical management of patients with ITP based on data presented at the 2021 European Hematology Association (EHA) Virtual Congress.

Activity Summary:
Novel biomarker-driven approaches for the treatment of advanced/metastatic non-small cell lung cancer (NSCLC) continue to evolve at a rapid pace. Therefore, clinicians need to stay abreast with recently presented clinical trial data to provide updated molecular testing-based therapies for their patients with NSCLC.

These educational Clinical Clips will highlight important advances in biomarker-driven targeted therapy approaches for NSCLC based on data presented at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting.

Activity Summary:
These educational presentations will focus on issues related to HCV elimination among Appalachian community care providers. Topics discussed include approaches to identify patients at high risk, HCV screening and management strategies for persons who inject drugs and incarcerated persons, and gaps in the HCV care continuum and key tools that community healthcare professionals can use to achieve elimination goals within a clinical practice.

Dr. Sally Hodder and Dr. Alice Thornton will lead each of the 1-hour live webcast presentations along with a community expert in the each of the Appalachian regions. At the conclusion of the webcast a live question and answer session will be conducted. The activity will be available for 1 AMA/ANCC/ACPE credit hour based on confirmed participation and the completion of an evaluation and posttest.

Activity Summary:
Patient Perspectives in HIV: A CE Podcast Series is an accredited continuing education series of podcasts as downloadable audio files (MP3). These podcasts will be recorded and made available throughout the year. The content faculty and one of their patients will discuss considerations and challenges in managing HIV.

In this podcast, Dr. Monica Gandhi and a patient will discuss special considerations transgender patients may face in the treatment of HIV, the challenges faced by a person with HIV when interacting with their healthcare provider, and concerns and strategies in managing addiction.

Activity Summary:
These certified AMA/ANCC/ACPE interactive case presentations will review the latest management strategies and options for the prevention and treatment of HIV.

This interactive case review will use a case-based approach to discuss contemporary HIV management considerations in several patient case reviews, including recent release from incarceration, transgender patients, treatment naïve patients, and mental health concerns.

Activity Summary:
The Simply Speaking Hepatitis lecture series includes a curriculum that highlights the very latest clinical data utilizing a library of PowerPoint slide presentations developed and approved by key expert physicians and further reviewed and approved by the Planning Committee.

Activity Summary:
Improvements in the care of PAH patients depends on improving clinician awareness of the latest research into new diagnostic techniques, medications, and monitoring.

In this video, Dr. Robert Schilz and Dr. Victor Tapson discuss cutting-edge research in PAH to keep busy clinicians abreast of the current clinical data.