Activity Summary:
Immune thrombocytopenic purpura (ITP) is an acquired autoimmune disorder marked by reduced platelet counts, purpura, and bleeding episodes driven by antiplatelet autoantibodies. Diagnosis remains one of exclusion, requiring careful differentiation from other causes of thrombocytopenia. Advances in pediatric ITP treatment are ushering in an era of precision medicine, integrating novel immunomodulatory therapies and personalized treatment approaches to optimize patient care. Recent research has introduced targeted pharmacological agents that address immune dysregulation, refining treatment protocols to align with individual patient profiles. The evolving landscape of pediatric ITP care calls for a comprehensive, evidence-driven approach, combining established therapies with innovative strategies to enhance efficacy and long-term disease management.

In this lecture library, Dr. Cindy Neunert provides expert insights into emerging data on ITP pathophysiology, diagnosis, and treatment, equipping healthcare providers with the knowledge to translate new research into clinical practice and improve pediatric patient care.

Activity Summary:
Stroke prevention continues to challenge clinicians, especially when balancing effective anticoagulation with the risks of bleeding. During this video series, Drs C. Michael Gibson and Manesh Patel provide rapid updates on the latest science shaping stroke prevention. Each 10–15-minute episode delivers digestible insights on topics such as emerging anticoagulation strategies, residual stroke risk, and clinical trial takeaways. This series is perfect for time-pressed healthcare professionals as it offers actionable knowledge designed to support evidence-based decision-making.

Activity Summary:
Myasthenia Gravis (MG) has had significant advances, however critical gaps persist in optimizing care. Challenges include variability in diagnostic accuracy, particularly in seronegative cases, and a limited adoption of newer, more sensitive testing modalities. Additionally, the evolving treatment landscape—with emerging therapies such as complement inhibitors and FcRn antagonists—highlights the need for clinicians to stay informed about the latest evidence and integrate these options into personalized care strategies. Addressing these gaps is crucial to improving patient care, enhancing quality of life, and reducing the burden of long-term side effects associated with traditional treatments.

This special edition podcast series with Dr. Nicholas Silvestri enables healthcare providers to engage with evidence-based insights and practical guidance on MG management at their convenience. The podcast format is ideal for professionals to access while commuting, during breaks, or between patient appointments, providing targeted learning without disrupting their workflow.

Activity Summary:
Pulmonary hypertension among patients with interstitial lung diseases (ILD-PH) is associated with increased morbidity, mortality, and healthcare burden and is currently under-recognized in clinical practice. To improve outcomes, early detection, timely diagnosis, and treatment of this complication among patients with ILD is an urgent priority.

Throughout this case-based presentation, Dr. Jean Elwing informs and guides on the latest insights to screen for, detect, accurately diagnose, and assess the severity of ILD-PH. Dr. Elwing also includes a discussion on identifying the right time and patient for a right heart catheterization, as it represents a complex and confounding decision in current clinical practice.

Activity Summary:
Clinicians often encounter patients having complex clinical scenarios when managing PAH where diverse and dynamic diagnostic and therapeutic issues interact. In this advanced case-based presentation, Dr. Ronald Oudiz discusses complex clinical case scenarios to improve knowledge on the diagnosis and management of pulmonary arterial hypertension and its application in practice.

• Case 1: Newly Diagnosed PAH with Coexisting Connective Tissue Disease
• Case 2: PAH with Refractory Right Heart Failure (RHF) and Multiorgan Dysfunction
• Case 3: Methamphetamine-Associated PAH with Severe PH and Psychiatric Comorbidities
• Case 4: Pediatric PAH in a Child with Congenital Heart Disease and Postoperative Complications

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clip podcasts will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with "what you need to know" videos from data presented at IAS 2025.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with "what you need to know" videos from data presented at IAS 2025.

Activity Summary:
Immune thrombocytopenic purpura (ITP) is an acquired autoimmune disorder marked by reduced platelet counts, purpura, and bleeding episodes driven by antiplatelet autoantibodies. Diagnosis remains one of exclusion, requiring careful differentiation from other causes of thrombocytopenia. Advances in pediatric ITP treatment are ushering in an era of precision medicine, integrating novel immunomodulatory therapies and personalized treatment approaches to optimize patient care. Recent research has introduced targeted pharmacological agents that address immune dysregulation, refining treatment protocols to align with individual patient profiles. The evolving landscape of pediatric ITP care calls for a comprehensive, evidence-driven approach, combining established therapies with innovative strategies to enhance efficacy and long-term disease management.

In this podcast, Dr. Cindy Neunert, provides expert insights into emerging data on ITP pathophysiology, diagnosis, and treatment, equipping healthcare providers with the knowledge to translate new research into clinical practice and improve pediatric patient care.

Activity Summary:
The introduction of kinase inhibitors has significantly impacted the treatment landscape of plexiform neurofibromas (PN) associated with neurofibromatosis type 1 (NF1). In this podcast activity from the 2025 Annual Oncology Meeting, noteworthy data in NF1-PN has been summarized and evaluated by Dr. Amy Armstrong. This activity is AMA/ABS/ANCC/ACPE accredited for one-year.

Activity Summary:
During this educational podcast, Dr. Sonali Bose highlights the latest advances in COPD presented at the American Thoracic Society (ATS) International Conference in San Francisco, CA, May 17-21, 2025.

Noteworthy presentations, posters, and abstracts are presented from the conference that are of high clinical significance to improve COPD.

Activity Summary:
Chronic Obstructive Pulmonary Disease (COPD) remains a major global health burden with significant gaps in early diagnosis, personalized treatment, exacerbation prevention, and coordinated care. During this Clinical Clip video, Dr. Sonali Bose highlights the latest advances in COPD presented at the American Thoracic Society (ATS) International Conference in San Francisco, CA, May 17-21, 2025.

Activity Summary:
There continues to be significant progress in the treatment of primary biliary cholangitis (PBC) and these Clinical Clips from EASL 2025 have focused on the most impactful data presented at this conference. Dr. Nancy Reau will summarize key advances from EASL 2025 and describe their implications for clinical practice. 

Activity Summary:
There continues to be significant progress in the treatment of primary biliary cholangitis (PBC) and these Clinical Clips from EASL 2025 have focused on the most impactful data presented at this conference. Dr. Nancy Reau will summarize key advances from EASL 2025 and describe their implications for clinical practice. 

Activity Summary:
In this podcast titled "Emerging Evidence in Myasthenia Gravis: Key Updates from AAN 2025," Dr. Nicholas Silvestri provides healthcare professionals with an actionable update on recent advancements in MG; which features insights from groundbreaking research presented at AAN 2025.

Activity Summary:
In this Clinical Clip, Dr. Nicholas Silvestri provides a concise and clinically relevant summary of the most important emerging data presented at AAN 2025 that impact the management of generalized Myasthenia Gravis (gMG).

Topics covered include pivotal updates from recent clinical trials—such as MINT (inebilizumab), ADAPT NXT (efgartigimod), and MycarinG (rozanolixizumab)—highlighting the safety, efficacy, and practical implications of emerging therapies across diverse MG subtypes. The activity also explores trends in real-world treatment patterns, therapeutic inertia among neurologists, and new diagnostic approaches including advanced serologic testing and AI-supported electrophysiologic tools. With a focus on individualized care, this activity equips healthcare professionals with key insights to help integrate new therapies and diagnostic innovations into practice, ultimately supporting timely, targeted, and patient-centered management of MG.

Activity Summary:

We are pleased to have recently held the Optimal Management of HIV Disease & Hepatitis: Clinical Conference XXXIII (OPMAN). The conference took place March 22-23, 2025, in Washington, D.C., with leading clinicians and researchers presenting an array of topics covering HIV disease and liver disease. The presentations offered a unique distillation of clinically focused data tailored for practicing HIV and hepatitis healthcare professionals.

These accredited video archives of OPMAN XXXIII provide access to each day of the conference, including clinical presentations, interactive case discussions, and panel discussions addressing audience questions. Continuing education credit is provided for each segment, so you may participate in your area(s) of interest. We hope you enjoy this activity!

Activity Summary:
Managing psoriasis (PsO) and psoriatic arthritis (PsA) presents multiple challenges for healthcare professionals, including staying up to date with emerging therapies, recognizing early signs of PsA, managing comorbidities, and implementing multidisciplinary care strategies. Despite advances in biologic and systemic therapies, unmet needs persist in timely diagnosis, patient education, and comprehensive disease management. Busy healthcare professionals often lack the time for in-depth study of the latest research, creating a critical need for concise, accessible educational opportunities. These unmet needs point to the necessity of practical, time-efficient programs that provide actionable insights into new treatment protocols and improve patient outcomes.

These podcast episodes are designed to provide healthcare professionals with an in-depth exploration of the most recent advances in the management of psoriasis (PsO) and psoriatic arthritis (PsA). The segments will focus on key challenges in clinical practice, including early diagnosis, personalized treatment strategies, and the integration of patient-reported outcomes. It will also address the management of associated comorbidities and the latest therapeutic developments, including biologics and small molecules.

Activity Summary:
Managing psoriasis (PsO) and psoriatic arthritis (PsA) presents multiple challenges for healthcare professionals, including staying up to date with emerging therapies, recognizing early signs of PsA, managing comorbidities, and implementing multidisciplinary care strategies. Despite advances in biologic and systemic therapies, unmet needs persist in timely diagnosis, patient education, and comprehensive disease management. Busy healthcare professionals often lack the time for in-depth study of the latest research, creating a critical need for concise, accessible educational opportunities. These unmet needs point to the necessity of practical, time-efficient programs that provide actionable insights into new treatment protocols and improve patient outcomes.

These Mini-Modules are designed to provide healthcare professionals with an in-depth exploration of the most recent advances in the management of psoriasis (PsO) and psoriatic arthritis (PsA). The segments will focus on key challenges in clinical practice, including early diagnosis, personalized treatment strategies, and the integration of patient-reported outcomes. It will also address the management of associated comorbidities and the latest therapeutic developments, including biologics and small molecules.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational podcasts will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of "what you need to know" podcast episodes from data presented at CROI 2025.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of "what you need to know" videos from data presented at CROI 2025.

Activity Summary:
The Simply Speaking HIV lecture series includes a curriculum that highlights the very latest clinical data utilizing a PowerPoint slide presentation developed and approved by key expert physicians and further reviewed and approved by the Planning Committee. The slides will be continuously evaluated and updated for current relevance.

Activity Summary:
There has been unprecedented research progress in the treatment of hemophilia heralded by the development of non-replacement therapies, emerging factor mimetics, and novel gene therapy agents. In this podcast series, Dr. Jonathan C. Roberts and Dr. Mindy Simpson inform and guide on safely integrating recently approved agents into the treatment continuum while ensuring alignment with critical new breakthroughs and enabling patient-focused care pathways.

Activity Summary:
There has been unprecedented research progress in the treatment of hemophilia heralded by the development of non-replacement therapies, emerging factor mimetics, and novel gene therapy agents. In these mini-module episodes, Dr. Jonathan C. Roberts and Dr. Mindy Simpson inform and guide on safely integrating recently approved agents into the treatment continuum while ensuring alignment with critical new breakthroughs and enabling patient-focused care pathways.

Activity Summary:

Patients with interferon gamma (IFN–γ) driven diseases such as hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) face significant diagnostic and therapeutic challenges, with delays in diagnosis and limited effective treatments often resulting in poor outcomes. Despite advances in understanding the role of IFN-γ in these conditions, there remains an unmet need for more precise diagnostic tools and faster, targeted therapies to manage the hyperinflammatory states that characterize these diseases.

Activity Summary:

Patients with interferon gamma (IFN–γ) driven diseases such as hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) face significant diagnostic and therapeutic challenges, with delays in diagnosis and limited effective treatments often resulting in poor outcomes. Despite advances in understanding the role of IFN-γ in these conditions, there remains an unmet need for more precise diagnostic tools and faster, targeted therapies to manage the hyperinflammatory states that characterize these diseases.

Activity Summary:
What’s New Doc?: CAR T-cells in Multiple Myeloma, highlights key studies and publications from 2024 on the use of these agents in earlier lines of treatment. Dr. Mikhael details how approved and emerging CAR T cell agents in multiple myeloma will impact the treatment landscape and how to better integrate these agents to enable improved outcomes among patients.

Activity Summary:
There have been multiple key advances in the treatment landscape of chronic lymphocytic leukemia (CLL) in 2024. To that end, a number of double and triple combination studies have been completed or are currently underway and, innovative therapies such as bispecific antibodies and chimeric antigen receptor (CAR) T cells are being developed for CLL. In Highlights and Hindsight in CLL, Dr. Matthew Davids describes the most significant ongoing studies and publications in CLL from 2024 and details their impact on the treatment continuum. This activity enables participants to stay updated on the most relevant breakthroughs to improve outcomes among patients.

Activity Summary:
What’s New Doc?: CAR T-cells in Multiple Myeloma, highlights key studies and publications from 2024 on the use of these agents in earlier lines of treatment. Dr. Mikhael details how approved and emerging CAR T cell agents in multiple myeloma will impact the treatment landscape and how to better integrate these agents to enable improved outcomes among patients.

Activity Summary:
This podcast Clinical Clip features a leading expert highlighting the latest advances in Acute Myeloid Leukemia(AML) treatments presented at the 66th ASH Annual Meeting and Exposition from December 7-10, 2024, in San Diego, CA.

Activity Summary:

There have been multiple key advances in the treatment landscape of chronic lymphocytic leukemia (CLL) in 2024. To that end, a number of double and triple combination studies have been completed or are currently underway, and innovative therapies such as bispecific antibodies and chimeric antigen receptor (CAR) T cells are being developed for CLL. In Highlights and Hindsight in CLL, Dr. Matthew Davids describes the most significant ongoing studies and publications in CLL from 2024 and details their impact on the treatment continuum. This activity enables participants to stay updated on the most relevant breakthroughs and improve outcomes among patients.