New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering HIV data from January through March of 2022 will discuss the most clinically relevant information regarding PrEP, HIV cure, treatment experienced patients, long-acting ART and comorbidities.

Patient-focused care is the core of contemporary management of HIV. Understanding patient challenges as well as listening and learning about their concerns/barriers can improve HIV care outcomes and expectations. This case-based program will incorporate the patient voice into HIV management approaches for metabolic and cardiovascular comorbidities, long-term ART strategies, and transgender persons.

The state-of-the-art approach to HIV management continues to evolve as regular advances in basic science and clinical research lay the foundation for future trends. This program provides a forum for discussion of current controversies in the field, including vaccines and HIV, long-term HIV management, weight/metabolic considerations with ART, what antiretrovirals to select for women, and other hot topics in HIV clinical management.