Activity Summary:
The Pulmonary Hypertension Association (PHA)-Accredited PH Care Centers (PHCC) program began in late 2011 with the goal to raise the overall quality of care and improve outcomes in patients with this life-threatening disease. Accreditation is based on a center’s overall commitment to PH patients, breadth of health care professionals involved and scope of services provided. Two types of centers will be accredited: Centers of Comprehensive Care (CCC) and Regional Clinical Programs (RCP). Both will have demonstrated a commitment to providing expert-level care based on published consensus guidelines. PHCCs have the opportunity to enroll PH patients into the Pulmonary Hypertension Association Registry (PHAR) patient registry to evaluate trends and practice patterns to determine which treatments work best. Moreover, in the past two decades, research has vastly improved the understanding of the pathophysiology, diagnosis, and treatment of PAH. While no therapies have been approved to target new mechanisms of action in more than 15 years, multiple phase 2 and phase 3 clinical trials of novel therapies are underway. Therapeutic trials represent the front line of clinical progress, and becoming a clinical trial investigator in PH can further help deliver more life-changing therapies to patients with PH who need them.

This AMA/ANCC/ACPE accredited, on-demand video addresses some key questions on accredited PH Care Centers and what it takes to become a clinical trial investigator.

Activity Summary:
During this podcast series, Guy Young, MD, and Angela Weyand, MD, will inform and guide on keeping up with recent progress and safely integrating it into clinical treatment paradigms of severe hemophilia A. Topics covered include recent practice-changing updates in replacement and non-replacement therapies in hemophilia A, case presentations to aid in selecting the most appropriate treatment for diverse patients with severe hemophilia A, novel non-replacement therapy and gene therapy as well as case scenarios to examine the utility of gene therapy.

Activity Summary:
During this webcast archive, Dr. Angela Weyand and Dr. Guy Young will discuss the latest practice-changing updates and breakthroughs in hemophilia A treatment paradigms, to ultimately improve outcomes among patients.

Please see the downloadable slides as a resource for key discussion and teaching points.

Activity Summary:
Talking PAH is a webcast series that highlights the very latest clinical data in pulmonary arterial hypertension. Slides are developed and presented by leading PAH expert physicians and further reviewed and approved by the planning committee.

Pulmonary arterial hypertension (PAH) is a severe condition with a high mortality rate despite advances in diagnostic and therapeutic strategies. In recent years, significant scientific progress has been made in the understanding of the underlying pathobiological mechanisms with novel therapeutic compounds in development. In this on-demand video presentation, our PAH experts will review practice-changing results presented at the 2023 ATS, ERS, and CHEST meetings to assess their potential future incorporation into clinical practice for patients with PAH.

Activity Summary:
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a poor prognosis. New and emerging agents may fulfill an unmet need for patients with TNBC. Rapidly evolving evidence in TNBC can present challenges in aligning practice with the latest clinical data and guideline recommendations. This podcast series is designed to provide learners with the opportunity to enhance clinical decision-making skills about the diagnosis and management of TNBC. Participants will review the latest clinical evidence and patient management approaches in TNBC to enhance patient-centered care. Faculty will also discuss new strategies and approaches to reduce breast cancer mortality and improve the health outcomes of racial/ethnic groups.

Activity Summary:
During this accredited continuing education series of two (2) podcasts as downloadable audio files, Dr. Raj Chovatiya and Dr. David Rosmarin will provide expert interpretation of new data for current and emerging treatment options of vitiligo. Additionally, practical considerations for how new agents can impact patient outcomes will be discussed. Case presentations will be reviewed to help clinicians select the most appropriate treatment as well as address the significant health burdens and complications experienced by many patients during treatment.

Activity Summary:
The Simply Speaking HIV Prevention lecture series includes a curriculum that highlights the very latest clinical data utilizing a PowerPoint slide presentation developed and approved by key expert physicians and further reviewed and approved by the Planning Committee. The slides will be continuously evaluated and updated for current relevance.

Activity Summary:
During this webcast archive, Dr. Raj Chovatiya and Dr. David Rosmarin provide expert interpretation of new data for current and emerging treatment options of vitiligo, along with practical considerations for how new agents can impact patient outcomes. Case presentations will be discussed to help clinicians select the most appropriate treatment as well as address the significant health burdens and complications experienced by many patients during treatment.

Please click the ‘Download Slides’ or ‘View Slides' button for access to the supplemental slides as your educational resource.

Activity Summary:
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a poor prognosis. New and emerging agents may fulfill an unmet need for patients with TNBC. Rapidly evolving evidence in TNBC can present challenges in aligning practice with the latest clinical data and guideline recommendations. This virtual roundtable conversation is designed to provide learners with the opportunity to enhance clinical decision-making skills about the diagnosis and management of TNBC. Participants will review the latest clinical evidence and patient management approaches in TNBC to enhance patient-centered care. Faculty will also discuss new strategies and approaches to reduce breast cancer mortality and improve the health outcomes of racial/ethnic groups.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering HIV data from July through September of 2023, will discuss the most clinically relevant information on HIV Prevention, ART Studies: Treatment-Naive, ART Studies: Treatment-Experienced and 4. Cardiometabolic Considerations and Other HIV Studies.

Activity Summary:
Clinical Clips are accredited, on-demand video presentations that feature experts discussing recent clinical updates, hot topics and treatment options. This activity is designed to keep healthcare professionals on top of the most recent clinical findings.

This stand alone certified AMA/ANCC/ACPE enduring video will spotlight latest advances in the management of non-small cell lung cancer harboring EGFR Mutations through a 'what you need to know' video featuring a leading expert reporting from the 2023 ESMO Congress.

Activity Summary:
Patient Voices in HIV Management: A CE Podcast Series is an accredited continuing education series of podcasts as downloadable audio files (MP3). These podcasts will be recorded and made available throughout the year.

In this series of podcasts, the content faculty and one of their patients will discuss considerations and challenges in the prevention and treatment of HIV. Topics covered will include patient concerns, benefits and risks of antiretroviral therapy, and how patients have handled challenges in their HIV management.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of ‘what you need to know’ videos from data presented from the 2023 European AIDS Clinical Society Conference.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of ‘what you need to know’ videos from data presented from IDWeek 2023.

Activity Summary:
Despite dramatic advances in the development of treatments for pulmonary arterial hypertension (PAH), it remains a chronic life-threatening illness for which there is no cure. Advances in knowledge within the field are eagerly anticipated.

These educational Clinical Clips will spotlight important research into the basic science, diagnosis, treatment, and medical management of patients with PAH based on data presented at the American College of Chest Physicians (CHEST) Annual Meeting in Honolulu, HI, October 8-11, 2023.

Activity Summary:
This program will use a case-based format that incorporates the patient voice to discuss patient treatment concerns, translatability of recent study results to clinical practice, and management strategies to improve patient outcomes.

As our understanding of HIV and HIV therapy progress, so do our management approaches. Learning about concerns/barriers that patients with HIV face can lead to improved individualized outcomes as well as place the healthcare professional at the forefront of HIV care.

Activity Summary:
Conversations in Hematology/Oncology: Evolving Role of Bispecific Antibodies in B-cell Non-Hodgkin Lymphomas (B-NHL) is a roundtable discussion between leading experts to inform clinical practice about the rationale, safety, and efficacy of bispecific antibodies in B-NHL. The expert faculty will provide guidance on how to safely optimize therapy with bispecific antibodies to improve outcomes among patients. The activity will be supported by downloadable slides that have the key discussion/teaching points.

Activity Summary:
Clinical Viewpoints HLH/MAS includes a curriculum that highlights the very latest clinical data in hemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS). Slides are developed and updated throughout the year by leading HLH/MAS expert physicians. All content is reviewed and approved by the Clinical Viewpoints HLH/MAS Planning Committee.

The current initial treatment for hemophagocytic lymphohistiocytosis (HLH) and/or macrophage activation syndrome (MAS) aims to suppress the excessive activation of the immune system and treat the cytokine storm. However, contemporary HLH and MAS management is an evolving science that builds off each advance in basic/clinical research and clinical experience. This case-based slide kit discusses current controversies in the management of secondary HLH, including MAS.

Activity Summary:
Current guidelines recommend initial oral combination therapy for patients with low- or intermediate-risk pulmonary arterial hypertension (PAH) and initial combination therapy including intravenous prostacyclin for high-risk patients. These strategies are based on using regular multiparameter mortality risk assessments and proactive therapy escalation to achieve and maintain a low-risk status. This approach has been shown to slow disease progression, optimize clinical outcomes, and improve survival. Furthermore, as interest towards personalized medicine grows, a comprehensive understanding of patient phenotypes through multiomics approaches, called deep phenotyping, is needed to provide further insights on pathogenesis, diagnosis, prognosis and therapeutic outcomes.

This AMA/ANCC/ACPE accredited, on-demand video addresses some key questions on combination therapy and deep phenotyping featuring a PAH expert answering important commonly asked questions.

Activity Summary:
What’s New Doc? is an accredited, on-demand video presentation featuring a pulmonary arterial hypertension (PAH) expert answering important questions asked about PAH. Two AMA/ANCC/ACPE videos will be launched throughout 2023.

Activity Summary:
Clinical Viewpoints PH-ILD includes a curriculum that highlights the very latest clinical data in pulmonary hypertension due to interstitial lung disease (PH-ILD). Slides are developed and updated throughout the year by leading pulmonology expert physicians. All content is reviewed and approved by the Clinical Viewpoints PH-ILD Planning Committee.

Pulmonary hypertension among patients with interstitial lung diseases is associated with increased morbidity, mortality, and healthcare burden. To improve outcomes, early detection and treatment of this complication among patients with ILD is an urgent priority. This slide kit will inform and guide on the latest recommendations and methodologies to screen for, detect, and accurately diagnose PH-ILD. The best-practice approaches to further treat and manage patients with PH-ILD will also be detailed. The case-based format will address knowledge and competence deficits among healthcare professionals regarding the diagnosis and treatment of PH-ILD. Overall, this module will narrow or close existing gaps in care to enable improved outcomes among patients with PH-ILD.

Activity Summary:
Simply Speaking PAH includes a curriculum that highlights the very latest clinical data in pulmonary arterial hypertension (PAH). Slides are developed and updated throughout the year by leading PAH expert physicians. All content is reviewed and approved by the Simply Speaking PAH Planning Committee.

Recent progress in pulmonary arterial hypertension (PAH) is based on new strategies for combination therapy and on the escalation of treatments to improve the significant morbidity and mortality associated with this disease. This case-based slide kit is designed to discuss the importance of monitoring patients to determine when and how to optimally alter their PAH therapy. Case 1 discusses a newly diagnosed PAH patient with a review of diagnosis, risk assessments, and initial combination therapy strategies. Case 2 discusses a high-risk PAH patient with a review of disease progression, risk assessment and treatment escalation options.

Activity Summary:
Advances in HIV research often unfold rapidly. In order to deliver state-of-the-art care, healthcare providers who manage this patient population must stay abreast of data emerging from the major conferences.

These educational Clinical Clips will spotlight the latest advances in the treatment and prevention of HIV and related comorbidities with a series of ‘what you need to know’ videos from data presented from the 12th IAS Conference on HIV Science.

Activity Summary:
New frontiers for HIV therapy continue to be explored, as underscored by the clinical development and use of new agents, changing regimen strategies and development of long-acting novel agents. This expanding era of simplified and effective HIV therapy presents physicians with many new opportunities and challenges for providing care. To deliver state-of-the-art HIV prevention and care, healthcare providers must stay informed regularly of new clinical data and treatment recommendations in HIV.

This educational Quarterly Brief, covering HIV data from April through June of 2023, will discuss the most clinically relevant information ART Studies, Coinfections and Comorbidities, Women and HIV and Other Interesting HIV Research.

Activity Summary:
Simply Speaking PAH includes a curriculum that highlights the very latest clinical data in pulmonary arterial hypertension (PAH). Slides are developed and updated throughout the year by leading PAH expert physicians. All content is reviewed and approved by the Simply Speaking PAH Planning Committee.

Through patient cases, this slide kit provides learners with the opportunity to enhance clinical decision-making skills about the diagnosis and management of PAH. The module will take the learner through a complete virtual patient tour starting at the time of symptoms of PAH through diagnosis, evaluation, and how the disorder is managed. Case 1 will discuss how to manage the complications and precautions in a patient through pregnancy, labor and delivery, and the immediate postpartum period. Case 2 will discuss the common features of pediatric PAH with adult disease including the challenges that require unique approaches.

Activity Summary:
Quarterly Briefs on the Treatment for Early Lung Cancer: A Current Expert Analysis on Important Clinical Decisions is a video commentary discussing the latest study results, conference data and publications in targeted therapy and immunotherapy from the previous 3 months. The activity will be supported by downloadable slides that have the key discussion/teaching points.

Activity Summary:
Conversations and Updates in Gastric/GEJ Cancer is a roundtable discussion designed to inform and guide on the latest breakthroughs to improve patient outcomes.

This activity will involve discussion between key opinion leaders regarding the most recent advances in the second-line and subsequent treatment of gastric/GEJ cancer. The expert faculty will use case scenarios to enhance the learning experience and provide guidance on safely integrating recent progress into practice.

Activity Summary:
Conversations and Updates in Gastric/GEJ Cancer is a roundtable discussion designed to inform and guide on the latest breakthroughs to improve patient outcomes.

This activity will involve discussion between key opinion leaders regarding the most recent advances in the frontline treatment of gastric/GEJ cancer. The expert faculty will use case scenarios to enhance the learning experience and provide guidance on safely integrating recent progress into practice.

Activity Summary:
Conversations and Updates in Myelodysplastic Syndromes (MDS) is a roundtable discussion activity designed to inform and guide on the latest practice-changing insights to improve outcomes in both lower- and higher-risk MDS. The expert faculty presenters will discuss recent evidence and provide guidance on classifying, stratifying, and treating patients with MDS based on recent progress in the treatment continuum.

The activity is supported by downloadable slides that have the key discussion and teaching points.

Activity Summary:
Talking PAH is a webcast series that highlights the very latest clinical data in pulmonary arterial hypertension. Slides are developed and presented by leading PAH expert physicians and further reviewed and approved by the planning committee.

Over the past two decades, research has vastly improved the understanding of the pathophysiology, diagnosis, and treatment of pulmonary arterial hypertension (PAH). While no therapies have been approved to target new mechanisms of action in more than 15 years, multiple phase 2 and phase 3 clinical trials of novel therapies are underway. Further, management decisions regarding practical issues must also be addressed. Emerging research in accurate phenotyping of PH may also improve customization of therapies and prognostication as well as to increase the homogeneity of study cohorts in clinical trials. Improvements in the care of PAH patients depends on improving clinician awareness of the latest research into new diagnostic techniques, medications, and monitoring. This on-demand presentation is designed for the multi-disciplinary medical team and addresses the practical challenges of managing patients in the new era of PAH therapy.