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Over the past two decades, research has vastly improved the understanding of the pathophysiology, diagnosis, and treatment of pulmonary arterial hypertension (PAH). While no therapies have been approved to target new mechanisms of action in more than 15 years, multiple phase 2 and phase 3 clinical trials of novel therapies are underway. Further, management decisions regarding practical issues must also be addressed. Emerging research in accurate phenotyping of PH may also improve customization of therapies and prognostication as well as to increase the homogeneity of study cohorts in clinical trials. Improvements in the care of PAH patients depends on improving clinician awareness of the latest research into new diagnostic techniques, medications, and monitoring. This on-demand presentation is designed for the multi-disciplinary medical team and addresses the practical challenges of managing patients in the new era of PAH therapy.
Pulmonary arterial hypertension (PAH) is a progressive and fatal lung disease of multifactorial etiology. Current therapies for treating pulmonary hypertension aim to overcome the imbalance between vasoactive and vasodilator mediators and restore the endothelial cell function. Extensive research efforts have led to the emergence of innovative therapeutic approaches in the area of PAH. This on-demand video presentation will focus on several important aspects of PAH management, including a discussion of the challenges of diagnosing and treating patients, clinical trial data on emerging therapeutics for the management of PAH, and a review of strategies to optimize outcomes for patients with PAH.
These educational Clinical Clips will spotlight important research into the basic science, diagnosis, treatment, and medical management of patients with PAH based on data presented at key pulmonology conferences in 2023 through “What You Need To Know in 5-minutes” video clips. Clinical Clips are accredited for AMA/ANCC/ACPE accreditation with the completion of an evaluation and post-test.