Activity Summary:
During this podcast series, Guy Young, MD, and Angela Weyand, MD, will inform and guide on keeping up with recent progress and safely integrating it into clinical treatment paradigms of severe hemophilia A. Topics covered include recent practice-changing updates in replacement and non-replacement therapies in hemophilia A, case presentations to aid in selecting the most appropriate treatment for diverse patients with severe hemophilia A, novel non-replacement therapy and gene therapy as well as case scenarios to examine the utility of gene therapy.

Activity Summary:
During this webcast archive, Dr. Angela Weyand and Dr. Guy Young will discuss the latest practice-changing updates and breakthroughs in hemophilia A treatment paradigms, to ultimately improve outcomes among patients.

Please see the downloadable slides as a resource for key discussion and teaching points.

Activity Summary:
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a poor prognosis. New and emerging agents may fulfill an unmet need for patients with TNBC. Rapidly evolving evidence in TNBC can present challenges in aligning practice with the latest clinical data and guideline recommendations. This podcast series is designed to provide learners with the opportunity to enhance clinical decision-making skills about the diagnosis and management of TNBC. Participants will review the latest clinical evidence and patient management approaches in TNBC to enhance patient-centered care. Faculty will also discuss new strategies and approaches to reduce breast cancer mortality and improve the health outcomes of racial/ethnic groups.

Activity Summary:
Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a poor prognosis. New and emerging agents may fulfill an unmet need for patients with TNBC. Rapidly evolving evidence in TNBC can present challenges in aligning practice with the latest clinical data and guideline recommendations. This virtual roundtable conversation is designed to provide learners with the opportunity to enhance clinical decision-making skills about the diagnosis and management of TNBC. Participants will review the latest clinical evidence and patient management approaches in TNBC to enhance patient-centered care. Faculty will also discuss new strategies and approaches to reduce breast cancer mortality and improve the health outcomes of racial/ethnic groups.

Activity Summary:
Clinical Clips are accredited, on-demand video presentations that feature experts discussing recent clinical updates, hot topics and treatment options. This activity is designed to keep healthcare professionals on top of the most recent clinical findings.

This stand alone certified AMA/ANCC/ACPE enduring video will spotlight latest advances in the management of non-small cell lung cancer harboring EGFR Mutations through a 'what you need to know' video featuring a leading expert reporting from the 2023 ESMO Congress.

Activity Summary:
Conversations in Hematology/Oncology: Evolving Role of Bispecific Antibodies in B-cell Non-Hodgkin Lymphomas (B-NHL) is a roundtable discussion between leading experts to inform clinical practice about the rationale, safety, and efficacy of bispecific antibodies in B-NHL. The expert faculty will provide guidance on how to safely optimize therapy with bispecific antibodies to improve outcomes among patients. The activity will be supported by downloadable slides that have the key discussion/teaching points.

Activity Summary:
Clinical Viewpoints HLH/MAS includes a curriculum that highlights the very latest clinical data in hemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS). Slides are developed and updated throughout the year by leading HLH/MAS expert physicians. All content is reviewed and approved by the Clinical Viewpoints HLH/MAS Planning Committee.

The current initial treatment for hemophagocytic lymphohistiocytosis (HLH) and/or macrophage activation syndrome (MAS) aims to suppress the excessive activation of the immune system and treat the cytokine storm. However, contemporary HLH and MAS management is an evolving science that builds off each advance in basic/clinical research and clinical experience. This case-based slide kit discusses current controversies in the management of secondary HLH, including MAS.

Activity Summary:
Quarterly Briefs on the Treatment for Early Lung Cancer: A Current Expert Analysis on Important Clinical Decisions is a video commentary discussing the latest study results, conference data and publications in targeted therapy and immunotherapy from the previous 3 months. The activity will be supported by downloadable slides that have the key discussion/teaching points.

Activity Summary:
Conversations and Updates in Gastric/GEJ Cancer is a roundtable discussion designed to inform and guide on the latest breakthroughs to improve patient outcomes.

This activity will involve discussion between key opinion leaders regarding the most recent advances in the second-line and subsequent treatment of gastric/GEJ cancer. The expert faculty will use case scenarios to enhance the learning experience and provide guidance on safely integrating recent progress into practice.

Activity Summary:
Conversations and Updates in Gastric/GEJ Cancer is a roundtable discussion designed to inform and guide on the latest breakthroughs to improve patient outcomes.

This activity will involve discussion between key opinion leaders regarding the most recent advances in the frontline treatment of gastric/GEJ cancer. The expert faculty will use case scenarios to enhance the learning experience and provide guidance on safely integrating recent progress into practice.

Activity Summary:
Conversations and Updates in Myelodysplastic Syndromes (MDS) is a roundtable discussion activity designed to inform and guide on the latest practice-changing insights to improve outcomes in both lower- and higher-risk MDS. The expert faculty presenters will discuss recent evidence and provide guidance on classifying, stratifying, and treating patients with MDS based on recent progress in the treatment continuum.

The activity is supported by downloadable slides that have the key discussion and teaching points.

Activity Summary:
Conversations in High-Risk NMIBC is a roundtable discussion featuring a urologist and two oncologists. The expert faculty will detail and reflect on recent advances in the treatment and management of high-risk NMIBC.

The activity will be supported by downloadable slides that have the key discussion and teaching points.

Activity Summary:
Talking Hemophilia A is a roundtable discussion continuing education activity designed to inform and guide on integrating novel therapies into hemophilia A treatment paradigms.

The expert faculty presenters will provide an overview of existing approaches and their limitations and how new and emerging therapies can be used to address unmet needs. The activity will be supported by downloadable, supplemental slides that have the key discussion and teaching points.

Activity Summary:
Despite advances in the initial treatment strategies of multiple myeloma, many patients will experience an early relapse. The further management of such patients can be challenging given the various options and complex patient- and disease-related factors.

Conversations and Cases in Multiple Myeloma is a roundtable discussion activity designed to inform and guide on integrating recent progress in the management of early relapse. The expert faculty will discuss different cases with early relapse and provide guidance on safely using approved and emerging therapy to improve outcomes. The activity will be supported by downloadable slides that have key discussion and teaching points.

Activity Summary:
Lightning Reports are accredited, on-demand video presentations that feature experts discussing recent clinical updates, hot topics and treatment options. These activities are designed to keep healthcare professionals on top of the most recent clinical findings.

This series of accredited continuing education enduring videos will provide brief commentary spotlighting hot topics in myelodysplastic syndromes (MDS) presented at the 2022 American Society for Hematology (ASH) Annual Meeting from New Orleans, Louisiana.

Activity Summary:
Conversations and Updates in Gastric/GEJ Cancer is a roundtable discussion designed to inform and guide on the latest breakthroughs to improve patient outcomes.

Through patient cases and scenarios, the expert faculty presenters will illustrate the integration of new evidence and biomarkers to safely treat and manage diverse patients with gastric/GEJ cancer. The activity will be supported by downloadable slides that have the key discussion/teaching points.

Activity Summary:
The Talking Post-Transplant Acute Myeloid Leukemia (AML) webcast series will provide recent updates to improve outcomes in post-transplantation relapse in AML.

This webcast series, led by expert faculty, will provide guidance and practical strategies to safely implement recent progress in addressing post-transplantation relapse in AML. Through patient cases and scenarios, faculty presenters will guide the integration of new evidence into clinical treatment paradigms of AML in the post-transplantation setting. The activity will be supported by downloadable slides that have the key discussion/teaching points.

*Healthcare providers may only claim for the participation of one (1) enduring archive activity.

Activity Summary:
The Talking Multiple Myeloma webcast archive will highlight recent advances in the initial management of multiple myeloma (MM).

Through patient cases and scenarios, the expert faculty presenters will discuss practice-changing updates in the initial management of MM, strategies to improve patient outcomes and prevent/manage adverse events as well as guide the integration of new evidence into clinical treatment paradigms.

Activity Summary:
With the recent approval of atezolizumab and osimertinib, and several ongoing trials, it has become clear that immunotherapy and targeted approaches are gaining ground in the adjuvant and neoadjuvant setting of early-stage non-small cell lung cancer (NSCLC). Considering the continual updates from clinical trials in this space, it is pivotal that healthcare professionals are familiar with the practical considerations to safely integrate this recent progress.

This activity will highlight the practice-changing updates in adjuvant and neoadjuvant approaches in early-stage NSCLC, to enable safe and effective implementation into clinical practice through expert-guided discussions with Drs. Julie Brahmer, Jamie Chaft and Stephen Liu.

Activity Summary:
Combining tyrosine kinase inhibitor and immunotherapy agents has shown considerable promise in Philadelphia positive acute lymphoblastic leukemia (Ph+ ALL). Although this approach can provide a chemotherapy-free and transplantation-sparing alternative, it is imperative that healthcare professionals are familiar with the practical considerations to safely integrate this recent progress.

This certified AMA activity will highlight the practice-changing updates in the frontline treatment of Ph+ ALL and provide guidance on effective implementation of new evidence through expert-guided discussions and interactive case scenarios.

Activity Summary:
Immune thrombocytopenic purpura (ITP) is a hematological autoimmune disorder characterized by low platelet count in the blood, which may lead to bruising and bleeding. For many years, immune-modulating therapies, such as corticosteroids, immunoglobulins (IVIG and anti-RhD), and rituximab, were the mainstays of treatment in ITP. Since 2008, the approval of thrombopoietin-receptor agonists (TPO-RAs) including a second-generation oral TPO-RA and a spleen tyrosine kinase (Syk) inhibitor, revolutionized the treatment landscape of ITP by opening new and highly effective avenues of treatment. This landscape will be further transformed with a sizable clinical pipeline including inhibitors of CD20, CD40, neonatal Fc receptor (FcRn), bruton’s tyrosine kinase (BTK), and Syk signaling.

This slide kit is designed to keep busy clinicians abreast of the emerging evidence for available treatments and the novel therapy pipeline, to optimize the treatment and care for patients with ITP.

Updated information is noted on the slide in the upper right hand corner. Please note that participants who have previously claimed credit for this activity should not claim duplicate credit based on the updates.

Activity Summary:
Lightning Reports are accredited, on-demand video presentations that feature experts discussing recent clinical updates, hot topics and treatment options. These activities are designed to keep healthcare professionals on top of the most recent clinical findings.

This series of certified AMA/ANCC/ACPE enduring videos will spotlight the latest advances in the management of bladder cancer through a series of ‘what you need to know’ videos featuring a leading expert reporting from the 2022 ASCO Annual Meeting.

Activity Summary:
Lightning Reports are accredited, on-demand video presentations that feature experts discussing recent clinical updates, hot topics and treatment options. These activities are designed to keep healthcare professionals on top of the most recent clinical findings.

This series of certified AMA/ANCC/ACPE enduring videos will spotlight the latest advances in the management of lung cancer treated with targeted therapy through a series of ‘what you need to know’ videos featuring a leading expert reporting from the 2022 ASCO Annual Meeting.

Activity Summary:
Lightning Reports are accredited, on-demand video presentations that feature experts discussing recent clinical updates, hot topics and treatment options. These activities are designed to keep healthcare professionals on top of the most recent clinical findings.

This series of video highlights will cover bladder cancer and targeted therapy in lung cancer based on data presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting.